セミナー
698 イベント
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Magnonic spin current and shot noise in an itinerant Fermi gas
2024年6月25日(火) 13:30 - 15:00
テイユ・チョウ (東京大学 大学院理学系研究科 物理学専攻 博士課程)
Spin transport phenomena at strongly-correlated interfaces play central roles in fundamental physics as well as spintronic applications. Although the spin-flip tunneling process, a key mechanism of spin transport, has been extensively studied in solid-state systems, its behavior in itinerant Fermi gases remains elusive. In this regard we study the spin tunneling in a repulsively interacting ultracold Fermi gas based on the conventional quasiparticle tunneling process. we investigate the spin current induced by quasiparticle and spin-flip tunneling processes to see their bias dependence and interaction dependence. To anatomize spin carriers, we propose the detection of the spin current noise in the system. The Fano factor, which is defined as the ratio between the spin current and its noise can serve as a probe of elementary carriers of spin transport. The change of the Fano factor microscopically evinces a crossover from the quasiparticle transport to magnon transport in itinerant fermionic systems.
会場: セミナー室 (359号室) 3階 359号室とZoomのハイブリッド開催
イベント公式言語: 英語
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セミナー
Grassmann Tensor Renormalization Group for two-flavor Schwinger model with a theta term
2024年6月24日(月) 16:00 - 17:00
菅野 颯人 (理化学研究所 仁科加速器科学研究センター (RNC) 理研BNL研究センター 理論研究グループ 基礎科学特別研究員)
QCD has been understood through numerical calculations by the Monte Carlo method. However, this method does not work for some parameter regions because of the sign problem. For example, QCD with a theta term has a sign problem, so the nature of QCD with a finite theta parameter is unknown. The theta dependence is also important to axion physics. To reveal such systems, tensor network methods are powerful tools. Tensor network methods have been developed by condensed matter theorists. Furthermore, recently there have been some attempts to apply them to high energy physics. In particular, the tensor renormalization group (TRG) method is remarkable for its applicability to higher dimensions. The Schwinger model is known as a two-dimensional toy model of QCD. It has the chiral symmetry and theta term as the same as QCD. In this study, the free energy of the two-flavor Schwinger model is calculated in a broad range of mass and theta parameters. We use TRG to calculate it, with obvious 2pi periodicity of theta parameter. We check the consistency with analytical values in large and small mass limits.
会場: via Zoom / セミナー室 (359号室)
イベント公式言語: 英語
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セミナー
Finding and understanding disease-causing genetic mutations
2024年6月20日(木) 16:00 - 17:00
小嶋 将平 (理化学研究所 生命医科学研究センター (IMS) ゲノム免疫生物学理研白眉研究チーム 基礎科学特別研究員)
Disease is caused by genetic factors and environmental factors. Genome-wide association study (GWAS) is a powerful method to find genetic factors associated with disease and human complex traits. One conceptual finding GWAS revealed is that many common diseases are caused by a combination of multiple genetic factors (polygenic), rather than a single causal mutation (monogenic). I have been working on finding genetic factors causing polygenic diseases by developing software that accurately finds sequence insertions and deletions from human population-scale sequencing datasets. In this talk, first, I will introduce some examples of disease-causing variants we recently discovered. Next I will also introduce my current research theme aiming to untangle how multiple genetic factors coordinately change cellular homeostasis, which I would like to have a collaboration with mathematical scientists.
会場: 研究本館 3階 359号室とZoomのハイブリッド開催
イベント公式言語: 英語
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セミナー
Quantum Computation Study Group Seminars
2024年6月18日(火) 13:30 - 15:00
菊池 勇太 (クオンティニュアム株式会社)
エルマル・ルラーバイ (HPC Architecture and Performance Engineer, National Energy Research Scientific Computing Center (NERSC), Lawrence Berkeley National Laboratory (LBNL), USA)Speaker: Yuta Kikuchi Title: Simulating Floquet scrambling circuits on trapped-ion quantum computers Abstract: Complex quantum many-body dynamics spread initially localized quantum information across the entire system. Information scrambling refers to such a process, whose simulation is one of the promising applications of quantum computing. We demonstrate the Hayden-Preskill recovery protocol and the interferometric protocol for calculating out-of-time-ordered correlators to study the scrambling property of a one-dimensional kicked-Ising model on 20-qubit trapped-ion quantum processors. The simulated quantum circuits have a geometrically local structure that exhibits the ballistic growth of entanglement, resulting in the circuit depth being linear in the number of qubits for the entire state to be scrambled. We experimentally confirm the growth of signals in the Hayden-Preskill recovery protocol and the decay of out-of-time-ordered correlators at late times. As an application of the created scrambling circuits, we also experimentally demonstrate the calculation of the microcanonical expectation values of local operators adopting the idea of thermal pure quantum states. Speaker: Ermal Rrapaj Title: Exact block encoding of imaginary time evolution with universal quantum neural networks Abstract: Quantum computers have been widely speculated to offer significant advantages in obtaining the ground state of difficult Hamiltonian in chemistry and physics. The imaginary-time evolution method is a well-known approach used for obtaining the ground state in quantum many-body problems on a classical computer. In this work we develop a practical method for such purpose. We develop a constructive approach to generate quantum neural networks capable of representing the exact thermal states of all many-body qubit Hamiltonians. The Trotter expansion of the imaginary-time propagator is implemented through an exact block encoding by means of a unitary, restricted Boltzmann machine architecture. Marginalization over the hidden-layer neurons (auxiliary qubits) creates the non-unitary action on the visible layer. Then, we introduce a unitary deep Boltzmann machine architecture, in which the hidden-layer qubits are allowed to couple laterally to other hidden qubits. We prove that this wave function ansatz is closed under the action of the imaginary-time propagator and, more generally, can represent the action of a universal set of quantum gate operations. We provide analytic expressions for the coefficients for both architectures, thus enabling exact network representations of thermal states without stochastic optimization of the network parameters. In the limit of large imaginary time, the ansatz yields the ground state of the system. The number of qubits grows linearly with the system size and total imaginary time for a fixed interaction order. Both networks can be readily implemented on quantum hardware via mid-circuit measurements of auxiliary qubits. If only one auxiliary qubit is measured and reset, the circuit depth scales linearly with imaginary time and system size, while the width is constant. Alternatively, one can employ a number of auxiliary qubits linearly proportional to the system size, and circuit depth grows linearly with imaginary time only.
会場: セミナー室 (359号室) 3階 359号室とZoomのハイブリッド開催
イベント公式言語: 英語
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The speciation-latitude relationship in ferns
2024年6月6日(木) 16:00 - 17:00
ホセ サイード・グティエレス オルテガ (数理創造プログラム 基礎科学特別研究員)
The latitudinal gradient of diversity (LGD), the pattern that shows that the highest numbers of species in major taxa are at low latitudes and that they decrease towards high latitudes, is the most conspicuous trend on the relationship between geography, environment, and biodiversity. But there is not a concrete answer of why it exists. Three hypotheses have been proposed so far: 1) tropics contain more species because communities have been climatically stable for longer time than the temperate areas; 2) the tropics receives more energy, which allows groups to diversify at higher rates; 3) the tropics provide a higher diversity of ecological opportunities for new species to specialize. By analyzing the fern community from the American continent, I tested the three hypotheses, and found that the first hypothesis is the most likely. The tropics contain more species not because they produce more species than the temperate areas, but because extinction has been lower historically. These results suggest that the climatic instability (cycles of interglaciation-glaciation) at high latitudes have shaped this curious pattern. I am using this seminar to show you some of my research progress, and to briefly mention some of the problems that I have encounter while trying to test my hypotheses. Maybe we can make some ideas to improve the methodological aspects of this kind of macro-ecological research
会場: via Zoom
イベント公式言語: 英語
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On the volume conjecture for the Teichm ̈uller TQFT
2024年5月31日(金) 15:00 - 17:00
上村 宗一郎 (数理創造プログラム 大学院生リサーチ・アソシエイト / 数理創造プログラム 研修生)
The Chern-Simons theory is a topological quantum field theory (TQFT) on the principal G-bundle and has been studied in both mathematics and physics. When G is SU(2), which is compact, Witten conjectured that its path integral gives the topological invariant of the base 3-manifold. This invariant was formulated rigorously and is known as the WRT invariant. In addition, it is known that the expectation value of the Wilson loop along the hyperbolic knot in S3 gives the invariant of knots, which is called the colored Jones polynomial. Invariants of knots and manifolds derived from the path integral are called quantum invariants. There is an open conjecture called the volume conjecture, which states that the complete hyperbolic volume of the knot complement appears in the asymptotic expansion of the colored Jones polynomial. The volume conjecture suggests a close connection between quantum invariants and hyperbolic geometry. On the other hand, Chern-Simons theory with the non-compact G such as SL(2,C) also appears in duality in string theory called the 3d-3d correspondence but has not been well formulated mathematically. Andersen and Kashaev constructed a TQFT-like theory called the Teichm ̈uller TQFT by quantizing the Teichm ̈uller space, which is the deformation space of the hyperbolic structures on a surface. The Teichm ̈uller TQFT is expected to correspond to the SL(2,C) Chern-Simons theory. In this theory, a conjecture similar to the volume conjecture has been proposed and proven for several hyperbolic knots. In this talk, I will introduce the outline of the Teichm ̈uller TQFT and explain our results on the volume conjecture and its proof using techniques in hyperbolic geometry by Thurston, Casson, Rivin, and others.
会場: via Zoom / セミナー室 (359号室)
イベント公式言語: 英語
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セミナー
Lipid Peroxidation Structure Selectivity: A Clue to Coal Workers' Pneumoconiosis
2024年5月30日(木) 16:00 - 17:00
Cai Tie (Associate Professor, China University of Mining and Technology, China)
Coal workers' pneumoconiosis (CWP), resulting from the inhalation of coal dust mixtures, is one of the leading occupational diseases globally. Despite its seriousness, there is still no effective curative method available for CWP. Therefore, a systemic understanding of CWP's pathogenesis is urgently needed. Peroxidation is an oxidation chain reaction in which lipids (glycerophospholipids and other membrane lipids) are degraded into excretory forms, such as fatty aldehydes. This process involves a series of enzymes that catalyze the reactions leading to lipid degradation. Our previous work identified specific regulatory mechanisms in lipid peroxidation processes triggered by diseases or various interventions. To gain a comprehensive understanding of lipid peroxidation, we developed a systematic profiling strategy that allows for the detailed observation of these oxidative processes. Additionally, we adapted this profiling strategy to investigate risk factors associated with coal workers' pneumoconiosis (CWP). By applying our methods to the study of CWP, we aimed to uncover the metabolic and molecular changes induced by coal dust inhalation, providing insights that could contribute to better prevention and treatment strategies for this occupational disease. To comprehensively investigate the lung alterations associated with CWP, both a cohort of coal miners and a CWP rat model were studied. Through the analysis of lipid peroxidation alterations associated with CWP occurrence, several CYP subtype-specific metabolic processes were identified. These findings suggest that coal-derived polycyclic aromatic hydrocarbons (PAHs) are major risk factors for CWP due to the specific activation of the Aryl Hydrocarbon Receptor (AhR) pathway. Further evidence at the gene level and morphological changes supports the role of coal-derived PAHs as key factors in the development of CWP. Hence, it is crucial to consider the toxicity induced by PAHs in the prevention and treatment of CWP.
会場: via Zoom
イベント公式言語: 英語
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Introduction to homotopy theory
2024年5月24日(金) 15:00 - 17:00
小泉 淳之介 (数理創造プログラム 基礎科学特別研究員)
In a narrow sense, homotopy theory is a framework for capturing the essential structures of shapes and has long been used as a powerful tool in topology. On the other hand, the concept of homotopy is so universal that it appears even in purely algebraic settings and has recently had a significant impact on other fields such as number theory and algebraic geometry. This talk aims to introduce homotopy theory in this broader sense from multiple perspectives. If time permits, I will also touch upon recent developments in the homotopy theory of algebraic varieties.
会場: via Zoom / セミナー室 (359号室)
イベント公式言語: 英語
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The collective order of human corneal endothelial cells as a unified biomarker for in vitro cultured cells and in vivo regenerated tissue
2024年5月23日(木) 16:00 - 17:00
山本 暁久 (数理創造プログラム 研究員)
Approximately 200,000 corneal transplantations are performed worldwide yearly, and more than half of them are applied to patients with corneal endothelial dysfunction. Recently, the restoration of functional corneas by injecting culture-expanded cells has developed in contrast to the conventional transplantation which relies on a limited number of donors’ corneas. This novel treatment opens up the potential to cure more patients with less surgical invasion and allows the utilization of cells with consistent and controlled quality. In this talk, I will introduce a unified physical biomarker for the quality assessment of corneal endothelial cells in in vitro culture and the predictive diagnosis of in vivo tissues using a single equation based on the collective order of cells. Taking an analogy to the two-dimensional colloidal assembly, the spatial arrangement of cells is generalized in terms of many-body interactions, and the “spring constant” of the underlying interaction potential is calculated from microscopy images. I also would like to discuss our recent approach to characterize the local structure of the arrangement of cells based on the topological data analysis.
会場: via Zoom
イベント公式言語: 英語
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セミナー
Prefactorization algebra and theta term
2024年5月21日(火) 16:00 - 17:30
川平 将志 (京都大学 基礎物理学研究所 博士課程)
Quantum field theories (QFTs) describe a lot of physical phenomena in our world. And giving a mathematical definition of QFTs is a long-standing problem. There are several mathematical formulations: Wightman formulation, Osterwalder–Schrader formulation and Atiyah-Segal formulation. And each of them cover different aspects of QFTs. Recently, Costello and their collabolators formulate QFTs by using prefactorization algbras. This formulaion cover a lot of classes of QFTs: TQFTs, 2d CFTs and perturbative QFTs. And they reproduce various results such as asymptotic freedom in non-Abelian gauge theories. Prefactorization algbras can be given by Batalin–Vilkovisky quantization (BV quantization) of the Lagrangian. However the original BV quantizations are perturbative and they do not have non-perturbative effects like instantons. In this talk, we propose the way to include Abelian-instanton effects. In modern language, it is the same as ℤgauging.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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Introduction to operator algebras
2024年5月17日(金) 15:00 - 17:00
北村 侃 (数理創造プログラム 基礎科学特別研究員)
I will give a quick introduction to operator algebras. Operator algebras in this talk consist of linear operators over some Hilbert space. Their study was initiated by Murray and von Neumann, motivated partially by the mathematical foundation of quantum mechanics. Starting from the definitions of a few basic notions, I will explain that commutative operator algebras can be interpreted as spaces. On the other hand, simple operator algebras (i.e., those without non-trivial ideals) form a class of operator algebras opposite to commutative ones and have attracted many operator algebraists. I will try to introduce several examples of simple operator algebras, some of which appear in mathematical physics. If time permits, I will also give recent results on ideals in C*-algebras. People with any scientific background are welcome.
会場: via Zoom / セミナー室 (359号室)
イベント公式言語: 英語
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セミナー
Exploring the impact of environments on flower color differentiation: A meta-analytical approach
2024年5月16日(木) 16:00 - 17:00
番場 大 (東北大学 大学院理学研究科 助教)
Flower color is one of the most diverse phenotypes in angiosperms, yet the initial processes of its differentiation remain unclear. Flower color is primarily expressed through the accumulation of pigment compounds in the petals, which are also associated with various stress responses. While it is conceivable that the environmental conditions during plant evolution could contribute to the differentiation of flower color, few studies have examined this hypothesis. Therefore, I conducted a meta-analysis using plant flower color information and growth environment data to elucidate the relationship between flower color differentiation and growth environments. Flower color data was extracted using LLM from botanical descriptions, and growth environment data was acquired by aligning GBIF occurrence information with WorldClim and ISRIC databases. Integrating approximately 30,000 flower color data points and 35 million occurrence records revealed trends such as a predominance of red flowers at higher altitudes and white flowers in arid areas. This study is still preliminary, so I would welcome discussions on more suitable analytical methods and models.
会場: via Zoom
イベント公式言語: 英語
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セミナー
Black hole graviton and quantum gravity
2024年5月16日(木) 15:00 - 16:30
木村 裕介 (理化学研究所 量子コンピュータ研究センター (RQC) 量子複雑性解析理研白眉研究チーム 研究員)
Drawing from a thought experiment that we conduct, we propose that a virtual graviton gives rise to a black hole geometry when its momentum surpasses a certain threshold value on the Planck scale. This hypothesis implies that the propagator of a virtual graviton, that possesses momentum surpassing this threshold, vanishes. Consequently, a Feynman diagram containing this type of graviton propagator does not add to the overall amplitude. This mechanism suggests the feasibility of formulating an ultraviolet-finite four-dimensional quantum gravitational theory. The elementary particles including the gravitons are treated as point particles in this formulation.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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セミナー
Boundary-induced transitions in Möbius quenches of holographic BCFT
2024年5月15日(水) 16:00 - 17:30
Dongsheng Ge (大阪大学 大学院理学研究科 特任研究員)
Boundary effects play an interesting role in finite-size physical systems. In this work, we study the boundary-induced properties of 1+1-dimensional critical systems driven by inhomogeneous Möbius-like quenches. We focus on the entanglement entropy in BCFTs with a large central charge and a sparse spectrum of low-dimensional operators. We find that the choice of boundary conditions leads to different scenarios of dynamical phase transitions. We also derive these results in a holographic description in terms of intersecting branes in AdS3, and find a precise match.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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セミナー
Quantum Computing in Omics Medicine
2024年5月10日(金) 16:00 - 17:15
角田 達彦 (東京大学 大学院理学系研究科 生物科学専攻 教授)
(The speaker is also the team leader of Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences. This is a joint seminar with the iTHEMS Biology Group.) In medical science, the recent explosive development of omics technologies has enabled the measurement not only of bulk data from entire tissues, but also data for individual cells and their spatial location information, and even allowed collection of such information in real-time. Meaningful interpretation of these rich data requires an ability to understand high-order and complex relationships that underpin biological phenomena such as drug response, simulating their dynamics, and selecting the optimal treatment for each patient based on these results. While these data are large-scale and of ultra-high dimensionality, they are also often sparse, with many missing values in the measurements and frequent higher-order interactions among variables, making them hard to handle with conventional statistics. To make further progress, machine learning – especially deep learning – is emerging as one of the promising ways forward. We have developed a method to transform omics data into an image-like representation for analysis with deep learning (DeepInsight) and have successfully used it to predict drug response and to identify original cell types from single-cell RNA-seq data. However, anticipation of the vast amount of medical data being accumulated gives particular urgency to addressing the problems of the time it actually takes to train deep learning models and the complexity of the necessary computational solutions. One possible way to resolve many of these problems is “quantum transcendence”, which is made possible by quantum superposition computation. Among all the different ways to apply quantum computation to medical science, we are particularly interested in quantum deep learning based on optimization and search problems, quantum modeling of single nucleotide detection by observational systems and statistical techniques such as regression analysis by inverse matrix computation and eigenvalue computation. In this seminar, I will first present an overview of how quantum machine learning and quantum deep learning can be used to formulate treatment strategies in medicine. We will discuss how to implement the quantum DeepInsight method, the challenges of noise in quantum computation when training QCNNs, feature mapping issues, problems of pretraining in quantum deep learning, and concerns relating to handling sensitive data such as genomic sequences. I hope this seminar will enhance our understanding of how to effectively facilitate medical research with quantum computing.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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セミナー
Surrogate Modeling for Supernova Feedback toward Star-by-Star Simulations of Milky-Way-sized Galaxies
2024年5月10日(金) 14:00 - 15:15
Keiya Hirashima (東京大学 大学院理学系研究科 天文学専攻 博士課程)
Galaxy simulations have found the interdependence of multiscale gas physics, such as star formation, stellar feedback, inflow/outflow, and so on, by improving the physical models and resolution. The mass resolution remains capped at around 1,000 solar masses (e.g., Applebaum et al. 2021). To overcome the limitations, we are developing a new N-body/SPH code, ASURA-FDPS, to leverage exascale computing (e.g., Fugaku), handle approximately one billion particles, and simulate individual stars and stellar feedback within the galaxy. However, the emergence of communication costs hinders scalability beyond one thousand CPU cores. One of the causes is short timescale events localized in tiny regions, such as supernova explosions. In response, we have developed a surrogate model using machine learning to duplicate supernova feedback quickly (Hirashima et al., 2023a,b). In the presentation, I report the fidelity and progress of the simulations with our new machine-learning technique.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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セミナー
Deep Learning for Estimating Two-Body Interactions in Mixed-Species Collective Motion
2024年5月9日(木) 16:00 - 17:00
上道 雅仁 (東京大学 大学院総合文化研究科 特任研究員)
(This is a joint seminar with the Information Theory Study Group.) Collective motion is a fundamental phenomenon observed in various biological systems, characterized by the coordinated movement of individual entities. Such dynamics are especially crucial in understanding cellular behaviors, which can now be observed at an individual level in complex tissue formations involving multiple types of cells, thanks to recent advancements in imaging technology. To harness this rich data and uncover the hidden mechanisms of such dynamics, we developed a deep learning framework that estimates equations of motion from observed trajectories. By integrating graph neural networks with neural differential equations, our framework effectively predicts the two-body interactions as a function of the states of the interacting entities. In this seminar, I will first introduce the structure and hyperparameters of our framework. Subsequently, I will detail two numerical experiments. The first is a simple toy model that was employed to generate data for testing our framework to refine the hyperparameters. The second explores a more complex scenario mimicking the collective motion of cellular slime molds, highlighting our model's ability to adapt to mixed-species interactions.
会場: 研究本館 3階 359号室とZoomのハイブリッド開催
イベント公式言語: 英語
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セミナー
Role of self-gravity on the central halo structure of fuzzy dark matter
2024年4月30日(火) 13:30 - 15:00
間仁田 侑典 (京都大学 基礎物理学研究所 協力研究員)
Fuzzy dark matter (FDM) is a dark matter model that is characterized by the ultralight masses around 10−22 eV. As FDM has the wave-like nature, the self-gravitating structure is described by the Schrödinger-Poisson equation. Previous simulations based on the Schrödinger-Poisson equation have demonstrated that soliton-like structure having a high-density flat core is formed at the central region of the FDM halos, and the size of such a core is typically determined by the de Broglie wavelength. Away from the central core, the density profile of the FDM halos resembles that of the cold dark matter halos on average, and is shown to be described by the Navarro-Frenk-White (NFW) profile. In this paper, we study the role of the self-gravity of the soliton core, and its relation to the bulk halo properties by solving the Schrödinger-Poisson equation in a simplified setup. The findings indicate that the contribution from the soliton self-gravity must dominate over the NFW potential in order to sustain the soliton.
会場: 研究本館 3階 359号室とZoomのハイブリッド開催
イベント公式言語: 英語
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セミナー
How Stars End Their Lives
2024年4月26日(金) 14:00 - 15:15
Philipp Podsiadlowski (Professor, University of Oxford, UK)
While the basic evolution of stars has been understood for many decades, there are still major uncertainties in our overall understanding of how stars end their lives, both in the context of low- and intermediate-mass stars (including the Sun) and massive stars. I will first review some of key principles that govern the structure and evolution of stars and then present recent progress that has been made for both groups of stars. I will argue and present numerical simulations that show that all stars become dynamically unstable when they become large giant stars, which leads to sporadic, dynamical mass ejections. Low- and intermediate-mass stars may lose all of their envelopes as a consequence, leaving white-dwarf remnants. More massive stars experience core collapse, leaving a neutron-star or black-hole remnant, possibly associated with a supernova explosion. I will show how the dramatic recent progress on understanding the core-collapse process, for the first time, allows us to connect the late evolution of massive stars with the resulting supernova explosions and the final remnants and discuss how observations with current gravitational-wave detectors (such as LIGO) will allow us to test this theoretical connection.
会場: セミナー室 (359号室) (メイン会場) / via Zoom
イベント公式言語: 英語
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Tracing link of cell ageing and disease progression: Joining factors and facilitators
2024年4月25日(木) 16:00 - 17:00
ラジクマール・シング カルラ (沖縄科学技術大学院大学 (OIST) 免疫シグナルユニット 研究員)
Cell ageing is an inevitable biological process. It marks declined homeostatic processes in a cell, the impact of which is reflected in the organism’s function/physiology. Ageing, thus, raises risks of disease progression in elderly people and compromises their immunity. Progression of cancer and neurodegenerative diseases and weak immune response against a pathogen(s) represent cases of ageing-related diseases. What molecular factors/signaling could be associated with disease progression or take part in governing such decisions in aging? – remained a key focus of my research so far. In my talk, I shall shed light on the part characterizing key proteins and their signalling in ageing-related diseases with an emphasis on cancer, neurodegenerative disease, and immunity. Taking advantage of wet lab and system biology studying gene networks, and genomic, proteomic, and metabolomic readouts, I investigated the molecular expression and processes impacted and compromised by ageing. I shall be discussing new knowledge from my work on the linkage of cell ageing and disease progression and therein role of key factors and facilitators I studied.
会場: via Zoom
イベント公式言語: 英語
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