Sustainable Organic Synthesis with Abundant Resources

The sustainable development of modern society necessitates technologies that harness earth-abundant metals and organic resources, minimizing reliance on scarce materials. This presentation will introduce our recent efforts towards this goal. We have developed sustainable organic synthesis using sodium dispersion, a molybdenum-quinone species for the diazo-free generation of carbene species from stable and readily available compounds, and a SpiroBpy ligand that enables the site-selective functionalization of arenes under remote steric control. I will also share some of the challenges we face in developing these reactions in order to ensure reproducibility.