Seminar

Phase Transitions as the Breakdown of Statistical Indistinguishability

June 29 (Mon) 15:00 - 16:00, 2026

Hideyuki Miyahara (Associate Professor, Graduate School of Information Science and Technology, Hokkaido University)

We introduce a novel characterization of phase transitions based on hypothesis testing. In our formulation, a phase transition is defined as the breakdown of statistical indistinguishability under vanishing parameter perturbations in the thermodynamic limit. This perspective provides a general, order-parameter-free framework that does not rely on model-specific insights or learning procedures. We show that conventional approaches, such as those based on the Binder parameter, can be reinterpreted as special cases within this framework. As a concrete realization, we employ a distribution-free two-sample run test and demonstrate that the critical point of the two-dimensional Ising model is accurately identified without prior knowledge of the order parameter.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Gravitational Properties of the Monopole Bag

June 23 (Tue) 13:30 - 15:30, 2026

Yu Komiya (Ph.D. Student, Yukawa Institute for Theoretical Physics, Kyoto University)

Processes such as phase transitions and symmetry breaking in the early universe are well-studied and thought to be instrumental in giving rise to the nature and composition that we observe. In particular, axionic cosmologies constitute a class of phenomenologically rich models with symmetry breaking, UV relevance, and potentially detectable consequences. In the case where monopoles are also present in such a background, the axion profile may be deformed; it is possible to construct a "monopole bag" state composed of a central monopole within a closed axion domain wall. We consider the gravitational properties of this hybrid defect, and find a both horizon-less and a black hole-like final state can result as remnants of the monopole-domain wall system after gravitational collapse for different input parameters

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Prediction of viral evolution and exploration of next-pandemic viruses

June 15 (Mon) 15:00 - 16:00, 2026

Jumpei Ito (Professor, Research Institute for Microbial Diseases, The University of Osaka)

One of the major challenges in controlling viral infectious diseases is that viruses continuously alter their properties through evolution. During the COVID-19 pandemic, for example, variants with enhanced immune escape and increased fitness emerged successively, thereby making epidemic control substantially more difficult. In this seminor, I will introduce our research on understanding and predicting viral evolution and epidemic dynamics by integrating protein language models, massive viral genome sequence data, and large-scale experimental datasets to model the relationships among viral genotypes, antigenicity, and fitness. Another major factor complicating the control of viral infectious diseases is the cross-species transmission of viruses harbored by wild animals to humans and livestock, leading to the emergence of novel infectious diseases. The COVID-19 pandemic, for instance, is thought to have originated from a coronavirus carried by horseshoe bats that subsequently spilled over into humans. To prepare for future pandemics, it is essential to comprehensively identify and systematically catalog viruses circulating in wildlife populations. In this seminar, I will also present our research on efficiently discovering novel viruses from massive public RNA-seq datasets by predicting viral infection based on host immune responses.

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Which Cosmological EFTs Survive the UV? A first step from quantum consistency to late-time cosmology

June 15 (Mon) 10:00 - 11:30, 2026

Carlos Pastor-Marcos (Ph.D. Student, ITP, Heidelberg University, Germany)

EFTs for cosmology are one of our best tools to describe possible departures from GR in the Universe we observe. However, not every low-energy theory can arise from a consistent quantum theory at high energies. In this talk, I will discuss how this question can be addressed using asymptotic safety (AS), and how UV consistency can constrain the space of viable modified-gravity EFTs. Instead of treating all EFT parameters as equally possible, we can ask which regions of theory space are connected to a well-defined fixed point in the UV. This provides the first ingredients of a UV-to-IR strategy, restricting the allowed low-energy theories and indicating how quantum-gravity information may reach cosmology. I will first give a pedagogical introduction to AS and the functional RG, focusing on the physical picture rather than technical details. I will then apply the framework to generalized Proca theories, a class of vector–tensor modified-gravity EFTs with relevant cosmological applications, to illustrate how this analysis is performed in practice and how it can constrain viable IR theories. I will close by discussing how UV completion can become a practical guide for cosmology, translating quantum-consistency conditions into phenomenological signatures, from late-time modified gravity to early-universe observables, strong-gravity tests and GW probes.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Noncritical Conformal Gravity and 4D Liouville Theory

June 12 (Fri) 15:00 - 16:30, 2026

Nobuyoshi Ohta (Visiting Professor, Nambu Yoichiro Institute of Theoretical and Experimental Physics (NITEP), Osaka Metropolitan University)

We study the quantum aspects of the conformal gravity in four dimensions, specifically addressing a known discrepancy in beta functions between general quadratic curvature theories and conformal gravity, which corresponds to two scalar degrees of freedom. We demonstrate that this mismatch is resolved by carefully introducing gauge-fixing and ghost terms via the BRST symmetry, which effectively adds the two scalar modes. Drawing lessons from two-dimensional quantum gravity and Liouville theory, we proceed to integrate the four-dimensional trace anomaly to derive a consistent Liouville action, which is given by a free-field action for the conformal mode with a consistent conformal anomaly. We give the condition that the BRST transformation is anomaly free. Finally I would like to talk about some application of this theory.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Testing quantum gravity

June 12 (Fri) 10:30 - 12:00, 2026

Daniel Carney (Scientist, Lawrence Berkeley National Laboratory (LBNL), USA)

I will give an overview of proposals to test the quantization of the gravitational field using terrestrial experiments. This will include gravitational entanglement experiments, "single-graviton detection" experiments, and searches for anomalous gravitational noise and decoherence.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Quantum Improved Black Holes in Asymptotically Safe Gravity

June 11 (Thu) 15:00 - 16:30, 2026

Chiang-Mei Chen (Professor, Department of Physics, National Central University, Taiwan)

In this talk, I will explore quantum-improved black hole solutions within the framework of asymptotic safety. In this approach, the Newton coupling becomes scale-dependent, necessitating a meaningful identification between the energy scale and a corresponding physical (length) scale to derive observable consequences for black hole spacetimes. I will argue that the requirement of consistency with the first law of black hole thermodynamics provides a physically motivated criterion for this scale-setting, particularly near the event horizon. Applying this principle, we propose a specific identification scheme that leads to a regularized geometry capable of resolving the ring singularity of Kerr black holes.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Disorder and Defects in Critical Systems

June 8 (Mon) 13:30 - 15:00, 2026

Baishali Roy (Postdoctoral Fellow, Indian Institute of Technology Kanpur, India)

Real critical systems are often constrained by boundaries and affected by impurities. In 3d, the effect of disordered impurities on the boundary can be modeled by a random magnetic field on a two-dimensional defect. In this talk, I will discuss how such disorder affects the Wilson-Fisher fixed point in d=4−\epsilon dimensions. By analyzing the one-loop RG flow of the defect couplings using the replica formalism, we find a non-trivial "dirty" fixed point which represents a new boundary universality class, stabilized by the bulk \phi^4 interaction. Disordered systems at critical points are known to exhibit logarithmic behavior — I will also discuss how operator mixing in the replica limit gives rise to a logarithmic defect CFT in our setup.

Venue: #359, 3F, Main Research Building (Main Venue) / via Zoom

Event Official Language: English

reflection positivity in de Sitter space

June 5 (Fri) 10:30 - 11:30, 2026

Yuki Suzuki (Ph.D. Student, Yukawa Institute for Theoretical Physics, Kyoto University)

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Membrane Geometry Regulates Phase Morphology in Postsynaptic Condensates

June 4 (Thu) 14:00 - 15:00, 2026

Risa Yamada (Ph.D. Student, Division of Biological Sciences, Graduate School of Science, Kyoto University)

Biomolecular condensates are generally regarded as membrane-less organelles formed through liquid–liquid phase separation (LLPS). However, some condensates in living cells emerge in close proximity to biological membranes, where spatial confinement and surface geometry can critically influence their organization and function. In this talk, I will discuss recent advances in understanding how membrane association regulates the phase behavior of postsynaptic density (PSD) condensates. Using mesoscale molecular simulations constrained by experimental interaction data, our study reproduced the distinct condensate architectures observed in solution and on membranes. In three-dimensional solution, AMPA receptor/PSD-95 complexes form the condensate core, whereas NMDA receptor/CaMKII complexes localize to the shell. Strikingly, this organization becomes reversed in membrane-associated two-dimensional systems. The analysis revealed that this transition arises from the competition between CaMKII’s large excluded volume and its highly multivalent interactions. While excluded-volume effects dominate in solution, membrane confinement favors specific multivalent interactions, stabilizing distinct receptor nanodomains. These results provide a physical framework for understanding how spatial dimensionality and molecular architecture regulate biomolecular condensates and synaptic organization.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

AI and Scientific Discovery

June 3 (Wed) 14:00 - 15:30, 2026

Joseph Ledsam (Google Health Lead, Japan, Google Japan)

Artificial intelligence is having a transformative impact on health and scientific discovery. This presentation will trace the evolution from foundational breakthroughs to the sophisticated capabilities of today's large-scale AI models. It will explore how these advanced systems are creating new possibilities across the healthcare landscape, from accelerating therapeutic development to enhancing diagnostic processes and interpreting complex medical data. The session will also take a deeper look at the future possibilities for AI in health and explore the emerging role of agentic AI in scientific discovery. The core theme is the responsible development of AI to create tools that assist scientists, support healthcare professionals, and empower users. Bio: Dr Joseph Ledsam leads Google Health in Japan, where he works across AI research, digital health and health in Google products. He has led research in medical AI, genomics and drug discovery published in journals including Nature, Nature Medicine and Nature Methods. Before moving to Japan he worked as a medical doctor in the UK, and founded the Health Research and Genomics teams in Google DeepMind. He obtained his medical degree from The University of Leeds, UK, and was a research fellow at University College London during his clinical residency.

Venue: #435-437, Main Research Building (Main Venue) / via Zoom

Event Official Language: English

Closed Seminar on Quantum Topology and Related Topics

May 29 (Fri) 14:00 - 18:00, 2026

Mao Hoshino (Special Postdoctoral Researcher, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))
Kan Kitamura (Assistant Professor, Department of Mathematics, College of Science, Rikkyo University)
Yuya Murakami (Research Scientist, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))
Vladimir Sosnilo (Research Scientist, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

We will hold a closed seminar on quantum topology and related topics. The talks will be given by the following four speakers. The talks will not be streamed online or recorded. 14:00–14:30 Mao Hoshino 14:30–15:00 Kan Kitamura (15:00–15:30 Coffee break) 15:30–16:00 Yuya Murakami 16:00–16:30 Vladimir Sosnilo (16:30–17:30 Casual reception)

Venue: Seminar Room #359

Event Official Language: English

Bootstrapping Cosmological Correlators

May 28 (Thu) 16:00 - 18:00, 2026

Mang Hei Gordon Lee (Post-Doctoral fellow, Leung Center for Cosmology and Particle Astrophysics, National Taiwan University, Taiwan)

Currently there are hundreds of models describing inflation, a period of accelerated expansion in our universe. Each model lead to different imprints in cosmological observables, and for the purpose of testing the idea of inflation itself, it is essential to understand which predictions are model independent. This lead to the idea of cosmological bootstrap, a set of constraints from physical principles and symmetries alone. In this talk I will give an overview on the cosmological bootstrap program. I will first explain how locality, unitarity and symmetry can constrain the kinematics of cosmological correlators. I will then talk about some recent progress on constructing positivity bounds on cosmology, which places constraints on the interactions of fields in inflation.

Venue: Hybrid Format (3F #359 and Zoom), Main Research Building

Event Official Language: English

Introduction to categorification and link homology

May 28 (Thu) 14:00 - 15:30, 2026

Mikhail Khovanov (Professor, Department of Mathematics, Johns Hopkins University, USA)

Quantum link invariants relate topology in 3 dimensions to mathematical physics and representation theory. They admit liftings to 4-dimensional structures, known as link homology. We will explain how the skein relations for quantum invariants turn into homological structures at this higher level and how semisimple representation theory turns into non-semisimple representations and homological algebra upon categorification.

Venue: Okochi Hall (Main Venue) / via Zoom

Event Official Language: English

Towards rock-solid evolutionary genomics

May 28 (Thu) 13:00 - 14:00, 2026

Leo Speidel (RIKEN ECL Research Unit Leader, Mathematical Genomics RIKEN ECL Research Unit, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

I will present an overview of ongoing and future projects in our lab. We aim to understand how human genomes retain information about our evolutionary past; a central goal is to reconstruct a high-resolution history of humans, pushing the limits of what we can learn about our origins, past migrations, and adaptation to changing environments and survival pressures. Our genomes reveal events that would otherwise be lost to history, revealing how evolutionary forces have shaped genetic variation and influence our health today. How can we confidently infer events that occurred tens of thousands of years ago? I will discuss how converging and independent lines of genomic evidence can provide “rock-solid” support for major evolutionary events, including archaic admixture, large-scale migrations across continents, and population bottlenecks, and how we aim to extend these approaches to study the evolutionary history and origins of humans and other species.

Venue: via Zoom / Seminar Room #359

Event Official Language: English

Cooperating on networks: inequality and social structure

May 27 (Wed) 14:00 - 15:00, 2026

Manuel Staab (Lecturer, University of Queensland, Australia)

We analyse how inequality in endowments and social structure jointly affect individuals' ability to cooperate. Individuals repeatedly invest in a local public good ("cooperation'') in an environment that is described by a distribution of endowments and a network of beneficiaries. We measure the cooperativeness of an environment by the minimum discount factor needed to sustain (any) cooperation in equilibrium. We characterise the endowment distribution that maximises cooperativeness for any given network and the corresponding minimum discount factor. The latter is shown to be inversely proportional to the maximal index of the graph describing the network. The corresponding dominant eigenvalue of the adjacency matrix characterises the most cooperative income distribution. Moreover, we show that if an environment maximises cooperativeness (over all income distributions and networks of a certain size), then the network is described by a nested split graph. We further show that this is the same class of graphs that maximise welfare for any given discount factor, and yet, the most cooperative graph need not be equal to the most efficient.

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English