Seminar

AI and Scientific Discovery

October 19 (Mon) 14:00 - 15:30, 2026

Joseph Ledsam (Google Health Lead, Japan, Google Japan)

Artificial intelligence is having a transformative impact on health and scientific discovery. This presentation will trace the evolution from foundational breakthroughs to the sophisticated capabilities of today's large-scale AI models. It will explore how these advanced systems are creating new possibilities across the healthcare landscape, from accelerating therapeutic development to enhancing diagnostic processes and interpreting complex medical data. The session will also take a deeper look at the future possibilities for AI in health and explore the emerging role of agentic AI in scientific discovery. The core theme is the responsible development of AI to create tools that assist scientists, support healthcare professionals, and empower users. Bio: Dr Joseph Ledsam leads Google Health in Japan, where he works across AI research, digital health and health in Google products. He has led research in medical AI, genomics and drug discovery published in journals including Nature, Nature Medicine and Nature Methods. Before moving to Japan he worked as a medical doctor in the UK, and founded the Health Research and Genomics teams in Google DeepMind. He obtained his medical degree from The University of Leeds, UK, and was a research fellow at University College London during his clinical residency.

Venue: #435-437, Main Research Building (Main Venue) / via Zoom

Event Official Language: English

Overview of quantum error correcting codes

July 7 (Tue) 15:00 - 16:30, 2026

Takaya Matsuura (Postdoctoral Researcher, Quantum Computing Theory Research Team, RIKEN Center for Quantum Computing (RQC))

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Toward an understanding of microbial circulation in the Mongolian nomadic ecosystem

July 6 (Mon) 13:00 - 14:00, 2026

Akari Shinoda (Assistant Professor, Faculty of Environmental, Life, Natural Science and Technology, Okayama University)

I have been studying microorganisms in the Mongolian nomadic ecosystem from several perspectives. First, I seek to characterize the microbial communities in traditional fermented dairy products—most notably airag (fermented mare's milk)—and their features. Second, I am analyzing the relationship between the traditional Mongolian diet and the gut microbiome. Third, focusing on environmental microorganisms (bioaerosols) in regions undergoing desertification, I aim to trace their origins and atmospheric transport. In the course of these studies, I have come to suspect that microorganisms may circulate among humans, livestock, fermented foods, and the environment. In this research, I aim to understand such microbial circulation by combining approaches from each of these perspectives and by investigating the relationships among these elements. In this talk, I will provide an overview of each topic and discuss the potential of an interdisciplinary approach that connects them.

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Thom polynomials relative to prescribed maps around the boundary

July 3 (Fri) 15:00 - 17:30, 2026

Masato Tanabe (Special Postdoctoral Researcher, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

Thom polynomials are universal cohomological obstructions to the appearance of singularities of given types in differentiable maps. Introduced by R. Thom in the 1950s, they have been extensively studied ever since. In the first half of this talk, I would like to recall their theory with introduction of algebro-topological materials. In the second half, I would also like to talk about applications of Thom polynomials to topology of non-singular maps. Since this century, various invariants of immersions/embeddings have been expressed in terms of singularities of their extensions (a.k.a. singular Seifert surfaces). However, those formulas are obtained in different forms and remain somewhat scattered. As the first step to unify them, I would like to introduce Thom polynomials relative to prescribed maps around the boundary. As a main result, we show a structure theorem of Thom polynomials relative to framable immersions. In fact, most earlier formulas are summarized as the vanishing of "correction terms" appearing in the structure theorem. This is an advanced seminar for mathematical researchers.

Venue: Seminar Room #359, Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Cosmic-ray bath in a past supernova gives birth to Earth-like planets

July 3 (Fri) 14:00 - 15:15, 2026

Ryo Sawada (Special Postdoctoral Researcher, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

A key question in astronomy is how ubiquitous Earth-like rocky planets are. The formation of terrestrial planets in our Solar System was strongly influenced by the radioactive decay heat of short-lived radionuclides (SLRs), particularly 26 Al (aluminum-26), likely delivered from nearby supernovae. However, current models struggle to reproduce the abundance of SLRs inferred from meteorite analysis without destroying the protosolar disk. We propose the "immersion" mechanism, where cosmic-ray nucleosynthesis in a supernova shockwave reproduces estimated SLR abundances at a supernova distance (~1 parsec), preserving the disk. We estimate that solar mass stars in star clusters typically experience at least one such supernova within 1 parsec, supporting the feasibility of this scenario. This suggests that Solar System─like SLR abundances and terrestrial planet formation are more common than previously thought.

Venue: #424-426, Main Research Building

Event Official Language: English

Phase Transitions as the Breakdown of Statistical Indistinguishability

June 29 (Mon) 15:00 - 16:00, 2026

Hideyuki Miyahara (Associate Professor, Graduate School of Information Science and Technology, Hokkaido University)

We introduce a novel characterization of phase transitions based on hypothesis testing. In our formulation, a phase transition is defined as the breakdown of statistical indistinguishability under vanishing parameter perturbations in the thermodynamic limit. This perspective provides a general, order-parameter-free framework that does not rely on model-specific insights or learning procedures. We show that conventional approaches, such as those based on the Binder parameter, can be reinterpreted as special cases within this framework. As a concrete realization, we employ a distribution-free two-sample run test and demonstrate that the critical point of the two-dimensional Ising model is accurately identified without prior knowledge of the order parameter.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Primitive Ideals and Hilbert Space Representations of Quantized Coordinate Algebras of Complex Semisimple Lie Groups

June 26 (Fri) 16:30 - 18:00, 2026

Heon Lee (Postdoc Researcher, Institute for Advanced Study in Mathematics, Harbin Institute of Technology, Republic of Korea)

The primitive ideals of the coordinate algebra $ \mathcal{O} ( G ) $ of a complex semisimple Lie group $ G $ are in bijection with the points of $ G $, via the correspondence assigning to each point of $ G $ the kernel of the associated evaluation homomorphism on $ \mathcal{O} ( G ) $. This establishes a direct link between the algebraic structure of $ \mathcal{O} ( G ) $ and the geometry of $ G $. In this talk, we investigate the quantum analogue of this classical relationship for the $ q $-deformation $ G_q $. Specifically, we establish a sharp dichotomy: primitive ideals in homogeneous Joseph strata arise as kernels of irreducible representations of $ \mathcal{O} ( G_q ) $ by bounded operators on Hilbert spaces, which provide a quantum analogue of evaluation homomorphisms at points of $ G $, whereas those in inhomogeneous Joseph strata do not. This clarifies the extent to which the primitive spectrum of $ \mathcal{O} ( G_q ) $ can be accessed through operator-theoretic methods. We also analyze the semiclassical consequences of this result in light of the fact that the primitive ideals of $ \mathcal{O} ( G_q ) $ are parametrized by the symplectic leaves of the natural Poisson structure on $ G $. This talk is based on joint work with Christian Voigt.

Venue: via Zoom / Seminar Room #359

Event Official Language: English

Symmetry origin of the quantum-classical transition, hydrodynamics, and decodability.

June 26 (Fri) 14:00 - 16:00, 2026

Cenke Xu (Professor, University of California, Santa Barbara, USA)

We discuss the following question: when a quantum system evolves into classical one, is there a sharp transition? We will show that the “strong-to-weak” spontaneous symmetry breaking (SW-SSB) provides a sharp onset of classical physics. We present the theoretical framework and summarize recent experimental progress toward observing SW-SSB. We will also discuss the consequence of the SW-SSB, including the emergence of hydrodynamics, and also its information aspect, such as the transition of decodability and distinguishability. Much of the theoretical analysis maps to a problem of defect in the Euclidean spacetime.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

Classical and quantum computing of Nash equilibria of two-player games

June 25 (Thu) 10:30 - 11:30, 2026

Erik Loetstedt (Senior Research Scientist, Quantum Mathematical Science Team, Division of Applied Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

Nash equilibrium is an important concept in game theory. However, finding mixed-strategy Nash equilibria is computationally hard even for relatively small games. I will review some aspects of the numerical computation of Nash equilibria of two-player games including the Lemke-Howson algorithm. I will also discuss preliminary attempts at solving the Nash equilibrium problem on a quantum computer by the quantum approximate optimization algorithm.

Venue: Seminar Room #359 (Main Venue) / via Zoom

Event Official Language: English

Fermionic modes of D-instanton wormholes from broken local supersymmetry

June 24 (Wed) 15:30 - 17:00, 2026

Hiroshi Itoyama (Specially Appointed Professor, Nambu Yoichiro Institute of Theoretical and Experimental Physics (NITEP), Osaka Metropolitan University)

In low-energy supergravity treatment of type IIB superstring on general D-instanton wormhole profiles in the bulk, we obtain non-vanishing scalar two-point functions in addition to the vanishing　〈τ＊τ＊〉 that corresponds to the BPS amplitude detected by two D-instantons at their respective boundaries. This is exploited to show that the modes of broken local supersymmetry in the bulk deliver the fermionic (diagonal) modes on the boundaries through the deformation by the form of current-current two point functions propagating on the tree level cylinder geometry. Our treatment is generalizable to multi D-instanton cases and general Euclidean branes.

Venue: #359, 3F, Main Research Building (Main Venue) / via Zoom

Event Official Language: English

Gravitational Properties of the Monopole Bag

June 23 (Tue) 13:30 - 15:30, 2026

Yu Komiya (Ph.D. Student, Yukawa Institute for Theoretical Physics, Kyoto University)

Processes such as phase transitions and symmetry breaking in the early universe are well-studied and thought to be instrumental in giving rise to the nature and composition that we observe. In particular, axionic cosmologies constitute a class of phenomenologically rich models with symmetry breaking, UV relevance, and potentially detectable consequences. In the case where monopoles are also present in such a background, the axion profile may be deformed; it is possible to construct a "monopole bag" state composed of a central monopole within a closed axion domain wall. We consider the gravitational properties of this hybrid defect, and find a both horizon-less and a black hole-like final state can result as remnants of the monopole-domain wall system after gravitational collapse for different input parameters

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359

Event Official Language: English

iTHEMS Cosmology Forum n°6 - Cosmological Collider Physics

June 22 (Mon) 9:15 - 17:00, 2026

Yi Wang (Professor, Department of Physics, Hong Kong University of Science and Technology, Hong Kong)
Masahide Yamaguchi (Director, Center for Theoretical Physics of the Universe, Institute for Basic Science, Republic of Korea)
Kyohei Mukaida (Assistant Professor, Theory Center, High Energy Accelerator Research Organization (KEK))
Kazuyuki Akitsu (R&D, Proxima Technology)

This sixth workshop will bring together researchers exploring the physics of the early universe through cosmological collider signatures. Primordial non-Gaussianities generated during inflation provide a unique opportunity to probe heavy particles and high-energy interactions in the early universe, potentially accessing energies much larger than that probed by terrestrial experiments. In recent years, the subject has developed rapidly, incorporating ideas from inflationary cosmology, quantum field theory in curved spacetime, effective field theory, and scattering amplitudes.

Venue: Okochi Hall

Event Official Language: English

The Virasoro TQFT approach to 3D gravity and the sum over topologies (QuIG Seminar)

June 19 (Fri) 13:30 - 16:00, 2026

Mengyang Zhang (Project Researcher, Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU), The University of Tokyo)

In the first part of this talk, I will review the construction of Virasoro TQFT from the Chern–Simons formulation of pure AdS_3 gravity and its application to the statistics of two-dimensional holographic CFT data. I will then discuss its extension to three-dimensional de Sitter gravity and its relation to the double-scaled SYK model. In the second part, I will address the issue of topological invariance in Virasoro TQFT. Despite being “topological,” its partition function is not well-defined on arbitrary three-manifolds, distinguishing it from conventional Reshetikhin–Turaev–Witten TQFTs. I will explain how far the standard proofs of topological invariance can be generalized to this framework. Finally, I will comment on the role of the sum over topologies in the 3D gravitational path integral.

Venue: via Zoom / #359, Main Research Building

Event Official Language: English

Improving data analysis in biology and in general with Tensor Decomposition

June 18 (Thu) 13:00 - 14:30, 2026

Lucas Sort (Postdoctoral Researcher, Mathematical Genomics RIKEN ECL Research Unit, Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS))

This talk will provide an introduction to the basic principles of tensor decomposition methods, especially CANDECOMP/PARAFAC (CP) decomposition. I will explain how such methods can be used to extract meaningful and interpretable patterns from high-dimensional tensor-structured data, which commonly arises in biology, as well as in a broad range of other scientific domains. These patterns can then be used to gain a better understanding of the phenomena under study. I will also briefly discuss how tensor decomposition methods can be extended for various types of data, focusing in particular on how I have been trying to better model longitudinal data.

Venue: via Zoom / Seminar Room #359

Event Official Language: English