March 31 (Thu) at 10:00 - 11:00, 2022 (JST)
  • Kyosuke Adachi (Special Postdoctoral Researcher, Nonequilibrium Physics of Living Matter RIKEN Hakubi Research Team, RIKEN Center for Biosystems Dynamics Research (BDR))
  • via Zoom

Several kinds of protein condensates have been observed in living cells, and the liquid-liquid phase separation is regarded as a basic mechanism of the condensate formation. However, given that there are thousands of protein species in a cell, it is not clear how the number and the composition of distinct condensates are controlled. One of the physics approaches to this problem is considering a model of many components with random interactions. In this Journal Club, I will introduce a recent paper [1] that applies random-matrix theory to the phase separation dynamics.


  1. K. Shrinivas, M. Brenner, Phase separation influids with manyinteracting components, Proc. Natl. Acad. Sci. U.S.A. 118, e2108551118 (2021), doi: 10.1073/pnas.2108551118