On Oct.26, the symposium "Can social issues be solved by mathematical science? -attempts and challenges" was held under the leadership of Takashi Sakajo (Kyoto Univ.) and Shingo Iwami (Nagoya Univ.) who are also iTHEMS colleagues. The symposium was held in a hybrid matter with more than 220 participants. After the presentations on various approaches to bridge the academia and industry, there were lively discussions on how to cross the valley between the mathematical science and social needs.