EFTs for cosmology are one of our best tools to describe possible departures from GR in the Universe we observe. However, not every low-energy theory can arise from a consistent quantum theory at high energies. In this talk, I will discuss how this question can be addressed using asymptotic safety (AS), and how UV consistency can constrain the space of viable modified-gravity EFTs. Instead of treating all EFT parameters as equally possible, we can ask which regions of theory space are connected to a well-defined fixed point in the UV. This provides the first ingredients of a UV-to-IR strategy, restricting the allowed low-energy theories and indicating how quantum-gravity information may reach cosmology.

I will first give a pedagogical introduction to AS and the functional RG, focusing on the physical picture rather than technical details. I will then apply the framework to generalized Proca theories, a class of vector–tensor modified-gravity EFTs with relevant cosmological applications, to illustrate how this analysis is performed in practice and how it can constrain viable IR theories. I will close by discussing how UV completion can become a practical guide for cosmology, translating quantum-consistency conditions into phenomenological signatures, from late-time modified gravity to early-universe observables, strong-gravity tests and GW probes.

Medical AI models often face performance degradation when applied to new patients due to inter-patient variability in physiological characteristics, disease manifestations, and clinical histories. This challenge, commonly referred to as the cross-patient problem, limits the generalizability and clinical applicability of machine learning systems.

We introduce a similarity-driven framework for patient-adaptive learning that improves model performance on previously unseen patients. The proposed approach first trains a base model using conventional supervised learning and subsequently estimates the similarity between a target patient and the training population using intermediate model representations. The similarity information is then incorporated into a fine-tuning procedure through patient-dependent weighting, enabling the model to adapt its decision boundaries toward the characteristics of each individual patient.

We demonstrate the effectiveness of this strategy in two medical AI applications, including seizure onset zone classification in epilepsy and medical image classification tasks. Experimental results show consistent improvements over standard cross-patient learning approaches, highlighting the potential of similarity-based adaptation as a practical solution for personalized and generalizable medical AI systems.

One of the major challenges in controlling viral infectious diseases is that viruses continuously alter their properties through evolution. During the COVID-19 pandemic, for example, variants with enhanced immune escape and increased fitness emerged successively, thereby making epidemic control substantially more difficult. In this seminor, I will introduce our research on understanding and predicting viral evolution and epidemic dynamics by integrating protein language models, massive viral genome sequence data, and large-scale experimental datasets to model the relationships among viral genotypes, antigenicity, and fitness.

Another major factor complicating the control of viral infectious diseases is the cross-species transmission of viruses harbored by wild animals to humans and livestock, leading to the emergence of novel infectious diseases. The COVID-19 pandemic, for instance, is thought to have originated from a coronavirus carried by horseshoe bats that subsequently spilled over into humans. To prepare for future pandemics, it is essential to comprehensively identify and systematically catalog viruses circulating in wildlife populations. In this seminar, I will also present our research on efficiently discovering novel viruses from massive public RNA-seq datasets by predicting viral infection based on host immune responses.

Understanding quantum gravity in de Sitter (dS) space remains a central challenge in cosmology and high-energy theory. While the dS/CFT proposal offers an organizing principle, its dual description is generically non-unitary, forcing us to rethink what we mean by dynamics, observables, and consistency when unitarity is not available. In parallel, condensed-matter theory has developed powerful frameworks for non-unitary physics via non-Hermitian Hamiltonians and field theories, revealing systematic structures such as complex spectra, biorthogonal formalisms, generalized symmetries (e.g., PT/pseudo-Hermiticity), exceptional points, and non-Hermitian topology. This workshop brings these communities together to test whether modern non-Hermitian tools can sharpen dS/CFT: clarifying the interpretation of non-unitary dynamics, identifying dS counterparts of non-Hermitian structures, and formulating concrete cross-field problems that can seed new collaborations.

Lecture II: Modern approach: Quantum instruments, POVMs, measuring processes, intersubjectivity, and value reproducibility

The modern approach to quantum measurement theory is based on the "realizability theorem" stating that a measurement is physically realizable if and only if its statistical properties are represented by a completely positive instrument, and this is also equivalent to saying that the measurement can be described by an interaction with a measuring apparatus (Ozawa 1984, 2004).

The conventional analysis of a measuring process determines the post-measurement object state by applying the "projection postulate" to the meter measurement in the post-measurement state that "entangles" the object and the apparatus, but the above result has been established without assuming the projection postulate altogether; rather we use only the classical Bayesian probability update rule (Ozawa 1984).

We introduce the "intersubjectivity theorem" that states that, when multiple observers simultaneously and statistically correctly measure the same physical quantity, they obtain the same measurement value and the "value reproducibility theorem" that states that a statistically correct measurement correctly reproduces the value of the physical quantity immediately before the measurement (Ozawa 2025).

The above three theorems essentially solves the so-called measurement problem, since we eliminate the collapse of the wave function and we establish the reality of the the pre-measurement value of the measured observable to be copied to the meter value and to be recorded by the observer.

In the first part of this talk, I will review the construction of Virasoro TQFT from the Chern–Simons formulation of pure AdS_3 gravity and its application to the statistics of two-dimensional holographic CFT data. I will then discuss its extension to three-dimensional de Sitter gravity and its relation to the double-scaled SYK model. In the second part, I will address the issue of topological invariance in Virasoro TQFT. Despite being “topological,” its partition function is not well-defined on arbitrary three-manifolds, distinguishing it from conventional
Reshetikhin–Turaev–Witten TQFTs. I will explain how far the standard proofs of topological invariance can be generalized to this framework.
Finally, I will comment on the role of the sum over topologies in the 3D gravitational path integral.

This sixth workshop will bring together researchers exploring the physics of the early universe through cosmological collider signatures. Primordial non-Gaussianities generated during inflation provide a unique opportunity to probe heavy particles and high-energy interactions in the early universe, potentially accessing energies much larger than that probed by terrestrial experiments. In recent years, the subject has developed rapidly, incorporating ideas from inflationary cosmology, quantum field theory in curved spacetime, effective field theory, and scattering amplitudes.

Processes such as phase transitions and symmetry breaking in the early universe are well-studied and thought to be instrumental in giving rise to the nature and composition that we observe. In particular, axionic cosmologies constitute a class of phenomenologically rich models with symmetry breaking, UV relevance, and potentially detectable consequences. In the case where monopoles are also present in such a background, the axion profile may be deformed; it is possible to construct a "monopole bag" state composed of a central monopole within a closed axion domain wall. We consider the gravitational properties of this hybrid defect, and find a both horizon-less and a black hole-like final state can result as remnants of the monopole-domain wall system after gravitational collapse for different input parameters

Lecture III: Measurement error, disturbance, the universally valid reformulation of Heisenberg’s uncertainty principle, and a quantitative generalization of the Wigner–Araki–Yanase theorem

Definitions of measurement error and disturbance are introduced (Ozawa 2002, 2019) and it is shown that there exists a solvable model for a physically realizable measurement that serves as a counterexample both to Heisenberg’s uncertainty principle in the conventional formulation and to the SQL (Ozawa 1988, 1989, 2002). Thus, those limits are no more considered as universal limits. In fact, the above counter example to SQL was found in 1988 using the idea of contractive state measurements by Yuen (1983) and the LIGO was started in 1994 to succeed in the gravitational wave detection in 2015 as announced in 2016.

New formulations are then proved for the uncertainty principle concerning the errors in the approximate simultaneous measurement of two physical quantities, called the "joint error relation" (Ozawa 2003b, 2004), and for the uncertainty principle concerning the error and disturbance associated with the measurement of a single physical quantity, called the "error-disturbance relation" (Ozawa 2003a). From the error-disturbance relation, a quantitative relation for measurement error under an additive conservation law is proved (Ozawa 2002a, 2003b), generalizing the "Wigner–Araki–Yanase theorem" (Wigner 1952, Araki-Yanase 1960), which states that a physical quantity not commuting with a conserved quantity cannot be measured accurately by a measurement interaction satisfying an additive conservation law. The above relation also derives limits for realizing quantum computing and operations under conservation laws (Ozawa 2002b), the results later developed as the resource theory of asymmetry.

In low-energy supergravity treatment of type IIB superstring on general D-instanton wormhole profiles in the bulk, we obtain non-vanishing scalar two-point functions in addition to the vanishing　〈τ＊τ＊〉 that corresponds to the BPS amplitude detected by two D-instantons at their respective boundaries. This is exploited to show that the modes of broken local supersymmetry in the bulk deliver the fermionic (diagonal) modes on the boundaries through the deformation by the form of current-current two point functions propagating on the tree level cylinder geometry. Our treatment is generalizable to multi D-instanton cases and general Euclidean branes.

We discuss the following question: when a quantum system evolves into classical one, is there a sharp transition? We will show that the “strong-to-weak” spontaneous symmetry breaking (SW-SSB) provides a sharp onset of classical physics. We present the theoretical framework and summarize recent experimental progress toward observing SW-SSB. We will also discuss the consequence of the SW-SSB, including the emergence of hydrodynamics, and also its information aspect, such as the transition of decodability and distinguishability. Much of the theoretical analysis maps to a problem of defect in the Euclidean spacetime.

The primitive ideals of the coordinate algebra $ \mathcal{O} ( G ) $ of a complex semisimple Lie group $ G $ are in bijection with the points of $ G $, via the correspondence assigning to each point of $ G $ the kernel of the associated evaluation homomorphism on $ \mathcal{O} ( G ) $. This establishes a direct link between the algebraic structure of $ \mathcal{O} ( G ) $ and the geometry of $ G $.
In this talk, we investigate the quantum analogue of this classical relationship for the $ q $-deformation $ G_q $. Specifically, we establish a sharp dichotomy: primitive ideals in homogeneous Joseph strata arise as kernels of irreducible representations of $ \mathcal{O} ( G_q ) $ by bounded operators on Hilbert spaces, which provide a quantum analogue of evaluation homomorphisms at points of $ G $, whereas those in inhomogeneous Joseph strata do not. This clarifies the extent to which the primitive spectrum of $ \mathcal{O} ( G_q ) $ can be accessed through operator-theoretic methods. We also analyze the semiclassical consequences of this result in light of the fact that the primitive ideals of $ \mathcal{O} ( G_q ) $ are parametrized by the symplectic leaves of the natural Poisson structure on $ G $.
This talk is based on joint work with Christian Voigt.

We introduce a novel characterization of phase transitions based on hypothesis testing. In our formulation, a phase transition is defined as the breakdown of statistical indistinguishability under vanishing parameter perturbations in the thermodynamic limit. This perspective provides a general, order-parameter-free framework that does not rely on model-specific insights or learning procedures. We show that conventional approaches, such as those based on the Binder parameter, can be reinterpreted as special cases within this framework. As a concrete realization, we employ a distribution-free two-sample run test and demonstrate that the critical point of the two-dimensional Ising model is accurately identified without prior knowledge of the order parameter.

Lecture IV: Instruments in classical mechanics, quantum field theory, and cognitive science

In algebraic quantum field theory, measurements describable by interactions between the field and the measuring apparatus are characterized by the class of completely positive instruments that satisfy the condition called the normal extension property (NEP) (Okamura-Ozawa 2016).

In classical mechanics, traditionally only non-invasive measurements—those with trivial interaction—were considered admissible, for the observability of the trajectory of motion. Here, however, the full class of measurements realizable by classical-mechanical interactions is characterized in terms of instruments with NEP for the basis of the study of invasive measurements of classical systems.

Cognitive processes are also represented by completely positive instruments, along with the long-standing paradigm provided by von Helmholtz, who described a sensation-perception process as a sort of measuring interaction and referred to it as an unconscious inference. This framework is used to show the compatibility of the question order effect and the response replicability effect (Ozawa-Khrennikov 2019), which failed to be explained in an earlier approach using only projective measurement models. It is shown that there exists an instrument model, realizing both the question order effect and the response replicability effect, that is also capable of almost faithfully reproducing public-opinion survey data such as the well-known Clinton-Gore survey by Gallup in 1997 (Ozawa-Khrennikov 2021).

A key question in astronomy is how ubiquitous Earth-like rocky planets are. The formation of terrestrial planets in our Solar System was strongly influenced by the radioactive decay heat of short-lived radionuclides (SLRs), particularly 26 Al (aluminum-26), likely delivered from nearby supernovae. However, current models struggle to reproduce the abundance of SLRs inferred from meteorite analysis without destroying the protosolar disk. We propose the "immersion" mechanism, where cosmic-ray nucleosynthesis in a supernova shockwave reproduces estimated SLR abundances at a supernova distance (~1 parsec), preserving the disk. We estimate that solar mass stars in star clusters typically experience at least one such supernova within 1 parsec, supporting the feasibility of this scenario. This suggests that Solar System─like SLR abundances and terrestrial planet formation are more common than previously thought.

Thom polynomials are universal cohomological obstructions to the appearance of singularities of given types in differentiable maps. Introduced by R. Thom in the 1950s, they have been extensively studied ever since. In the first half of this talk, I would like to recall their theory with introduction of algebro-topological materials.

In the second half, I would also like to talk about applications of Thom polynomials to topology of non-singular maps. Since this century, various invariants of immersions/embeddings have been expressed in terms of singularities of their extensions (a.k.a. singular Seifert surfaces). However, those formulas are obtained in different forms and remain somewhat scattered.

As the first step to unify them, I would like to introduce Thom polynomials relative to prescribed maps around the boundary. As a main result, we show a structure theorem of Thom polynomials relative to framable immersions. In fact, most earlier formulas are summarized as the vanishing of "correction terms" appearing in the structure theorem.

This is an advanced seminar for mathematical researchers.

Particle Physics is a study of the smallest and the biggest to uncover the fundamental laws that govern the universe. In recent years, both the United States and Europe have been through long-range planning processes. The future plans worldwide include the studies of (1) neutrinos that may have saved us from a complete annihilation, (2) the Higgs boson that keeps us in one piece, (3) dark matter that assembled us from the primordial soup, (4) inflation that created the macroscopic universe, and (5) the exploration of unknown particles and forces. It requires development of mind-boggling technologies.

iTHEMS-UTokyo Intensive Lectures on Quantum Gravity
(10th Quantum Gravity Gatherings Lecture Series)

The 10th QGG Lecture Series is a special three-day installment of the intensive lecture series organized by the Quantum Gravity Gatherings (QGG) study group at RIKEN iTHEMS. This celebratory edition will feature Professor Hikaru Kawai from Nambu Yoichiro Institute of Theoretical and Experimental Physics (NITEP), who will deliver a series of lectures on themes related to quantum gravity.

This lecture series will follow a style similar to Prof. Kawai's first QGG lectures, held three years ago at RIKEN (Wako) as the inaugural QGG event, which explored fundamental questions in quantum gravity, string theory, and the quantum universe. A distinctive feature of this 10th installment is that it will take place on the Komaba campus of The University of Tokyo, where one of the iTHEMS satellite offices is located. This will be the first QGG lecture series held outside Wako, with the aim of making the event more accessible to a broader group of participants.

Format:
Lectures will be given mainly in blackboard style and in English, encouraging active participation and in-depth Q&A discussions.
Poster sessions will also be held, giving participants an opportunity to present their own work or topics of interest. These sessions are intended to foster communication and stimulate the exchange of ideas among participants.

This event will take place in person only.

Target audience:
Senior scholars, early-career researchers, and students are all warmly welcome.

Registration deadline:
July 31, 2026

Workshop Overview
Majorana modes lie at the heart of contemporary condensed-matter physics, exhibiting non-Abelian exchange statistics; when protected by topology, they are robust against environmental perturbations. Here, “Majorana mode” is used broadly to include a localized zero-energy Majorana state (a Majorana zero mode) and chiral Majorana edge states with gapless dispersion crossing zero energy.

This three-day in-person workshop returns to fundamentals and open questions. It opens with a tutorial session on the afternoon of October 13 for non-experts and adjacent fields, and emphasizes rigorous theory–experiment dialogue, robust methodology, and concrete benchmarks for realizing and testing Majorana modes.

Participants
Experimentalists and theorists working on Majorana modes
Researchers in adjacent fields (quantum materials, superconductivity, mesoscopic physics)
Graduate students and postdocs interested in entering the field
Topics include (non-exhaustive)
Majorana zero modes in a variety of nanostructures
Chiral Majorana edge states in quantum spin liquids and other platforms
Disorder, interactions, and realistic device modeling
Experimental diagnostics and “smoking gun” signatures
Topological Quantum Spin Systems