Decoding Protein Condensation - Predicting Condensation of Proteins from Amino Acid Sequences -

The research team of Kyosuke Adachi (Research Scientist, iTHEMS / Research Scientist, Nonequilibrium Physics of Living Matter RIKEN Hakubi Research Team, RIKEN BDR) and Kyogo Kawaguchi (Team Leader, Nonequilibrium Physics of Living Matter RIKEN Hakubi Research Team, RIKEN BDR / Associate Professor, Institute for Physics of Intelligence, The University of Tokyo) has proposed a theory that predicts the condensation of protein molecules and demixing of condensates based on amino acid sequences.

This research is expected to contribute to elucidating the mechanisms for the formation of membraneless organelles in cells and, in the future, to develop into a theory that predicts the effect of mutations in proteins sequences on cellular functions.

For more details, please refer to the related link.