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iTHEMS Weekly News Letter

Press Release

Dr. Yuji Sakai thumbnail

Modeling the functions of condensin in chromosome shaping and segregation

2018-06-22

Former iTHES fellow, Yuji Sakai (Univ. Tokyo) together with Atsushi Mochizuki (iTHEMS), Masashi Tachikawa (iTHEMS), Tetsuya Hirano (RIKEN) and Kazuhisa Kinoshita (RIKEN) have published a paper and a press release.

Immediately before a cell divides, chromosomal DNA in a eukaryotic cell is packaged into a discrete set of rod-shaped chromosomes. This process, known as mitotic chromosome assembly or condensation, secures the faithful segregation of genetic information into daughter cells. Central to this mechanistically complex process is a class of protein complexes known as condensins. However, how condensins support the assembly and segregation of mitotic chromosomes at a mechanistic level remains elusive. Here we construct a coarse-grained physical model of chromosomal DNA fibers and condensin molecules, and study how condensins work in the mitotic chromosome assembly using computer simulations. Our results show that two activities of condensins, formation of consecutive loops in chromosomal DNA fibers and inter-condensin attractions, are necessary for both the shaping and segregation of mitotic chromosomes, and balancing acts of these activities help to coordinate the efficient progress of the processes. Importantly, chromosome shaping and segregation in our results are strongly correlated, implying that they are controlled by the same underlying mechanism mediated by condensins.

Upcoming Events

Math Lecture

Computational Algebraic Statistics and its Applications

June 26 at 10:00 - 16:30, 2018

Prof. Satoshi Aoki (Professor, Department of Mathematics, Kobe University)

Lecture 1 (10:00-11:30)
An introduction of Groebner bases of polynomial rings

Lecture 2 (13:00-14:30)
Groebner bases theory in design of experiments

Lecture 3 (15:00-16:30)
Groebner bases theory in sampling problems of contingency tables

This introductory lecture is about statistical theory from the point of view of the computational algebraic statistics, in particular the applications of Groebner bases. The statistical theory is a fundamental tool in natural science, social science and humanities, and the Groebner basis is a topic related to multi-variable polynomials. The Lecture will start from an introduction to the Groebner basis which would have wide applications in mathematics, physics, biology, chemistry, engineering, information science and computer science. Therefore, we welcome scientists in any field who are interested in this subject.

The event official language is Japanese (slides and writing are in English).

Venue: #535-537, 5F, Main Research Building, RIKEN

Event Official Language: Japanese

Seminar

​Denso IT Lab. and RIKEN Joint ​Innovation ​Seminar

June 29 at 16:00 - 17:40, 2018

16:00-17:00 Denso IT Laboratory
"About Denso IT lab." H. Iwasaki (Denso)
"Human-Car interface" ​H. Tsukahara​ (Denso)
​"Math in machine leaning and computer vision" K. Ishikawa (Denso)

17:00-17:40 RIKEN
"Math bridging between classical and quantum physics: quantum hall effect in classical system" T. Ozawa (RIKEN)
"Di-Omega: a new particle predicted by K-computer with mathematical science" S. Gongyo (RIKEN)

Venue: Common Room #246-248, 2F Main Research Building, RIKEN

Event Official Language: Japanese

Colloquium

iTHEMS Colloquium

Systems Biology of Cellular Rhythms

July 2 at 15:00 - 16:30, 2018

Prof. Albert Goldbeter (Professor, Unit of Theoretical Chronobiology, Faculty of Sciences, Université Libre de Bruxelles, Belgium)

Venue: Suzuki Umetaro Hall, 1F Bioscience Building, RIKEN

Broadcast: #305-2, Computational Science Research Building, R-CCS, Kobe Campus, RIKEN / SUURI-COOL (Kyoto), #204-205, 2F Maskawa Building for Education and Research, North Campus, Kyoto University / 2F Seminar Room, AIMR Main Building, Advanced Institute for Materials Research (AIMR), Tohoku University

Event Official Language: English

Seminar

Dr. Tomoki Ozawa thumbnail
AIMR Main Building venue photo

SUURI-COOL SeminarSUURI-COOL (Sendai)

Topological Photonics and the four-dimensional quantum Hall effect

July 3 at 15:00 - 17:00, 2018

Dr. Tomoki Ozawa (Senior Research Scientist, iTHEMS)

Venue: 1F Meeting Room, AIMR Main Building, Advanced Institute for Materials Research (AIMR), Tohoku University

Event Official Language: English

Workshop

Maskawa Building for Education and Research venue photo

Co-hosted by iTHEMSSUURI-COOL (Kyoto)

iCeMS-iTHEMS Joint Workshop on Interdisciplinary Biology

July 4 at 10:00 - 16:30, 2018

This is the first joint workshop between iCeMS (Kyoto Univ.) and iTHEMS (RIKEN). The WS is co-hosted by KUIAS (Kyoto Univ.), iTHEMS (RIKEN) and MACS Program (Kyoto Univ.). By exploring the forefront of experimental and mathematical biology, this workshop aims to stimulate novel research directions in these areas and strengthen the connection between Kyoto Univ. and RIKEN. Those who plan to attend the "get-together", please register before June 22 (Fri.) noon.

Co-hosted by
Kyoto University Institute for Advanced Study (KUIAS), Kyoto Univ.
Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS), RIKEN
MACS Program (MACS), Kyoto Univ.

Venue: #201, Maskawa Building for Education and Research, North Campus, Kyoto University

Event Official Language: English

Seminar

Dr. Tomoki Ozawa thumbnail

STAMP Seminar

Introduction to topological band structure

July 6 at 10:30 - 17:30, 2018

Dr. Tomoki Ozawa (Senior Research Scientist, iTHEMS)

Venue: Seminar Room #160, 1F Main Research Building, RIKEN

Event Official Language: Japanese

Math Lecture

Introduction to Public-Key Cryptography

Introduction to Public-Key Cryptography (6th)

July 11 at 10:30 - 12:00, 2018

Dr. Eren Mehmet Kıral (Visiting researcher, RIKEN Center for Advanced Intelligence Project)

Venue: Seminar Room #160, 1F Main Research Building, RIKEN

Event Official Language: English

Math Lecture

Dr. Yosuke Kubota thumbnail

Theory of Operator Algebras

Theory of Operator Algebras (3rd)

July 12 at 15:30 - 17:00, 2018

Dr. Yosuke Kubota (Research Scientist, iTHEMS)

Venue: Seminar Room #160, 1F Main Research Building, RIKEN

Event Official Language: English

Workshop

Co-hosted by iTHEMSSUURI-COOL (Kyoto)

The 9th RIKEN-Kyoto University Joint Data Assimilation Workshop

July 17 at 13:30 - 17:30, 2018

If you plan to attend the workshop, please register by July 13.

Hosted by Data Assimilation Research Team, RIKEN and Graduate School of Science, Kyoto University
Co-hosted by iTHEMS, RIKEN

Venue: #809 Graduate School of Science Bldg. No 6, Kyoto University

Event Official Language: Japanese

Colloquium

iTHEMS Colloquium

Bell's Theorem, Entanglement, Quantum Teleportation and All That

July 19 at 16:00 - 17:30, 2018

Prof. Anthony James Leggett (Professor, University of Illinois at Urbana-Champaign, USA)

iTHEMS-CEMS Joint Colloquium.

Professor Leggett is widely recognized as a world leader in the theory of low-temperature physics, and his pioneering work on superfluidity was recognized by the 2003 Nobel Prize in Physics.

Venue: Okochi Hall, 1F Laser Science Laboratory, RIKEN

Broadcast: #311, Computational Science Research Building, R-CCS, Kobe Campus, RIKEN / SUURI-COOL (Kyoto), #204-205, 2F Maskawa Building for Education and Research, North Campus, Kyoto University / 2F Seminar Room, AIMR Main Building, Advanced Institute for Materials Research (AIMR), Tohoku University

Event Official Language: English

Seminar

Number Theory Seminar

Number Theory Seminar

July 24 at 10:00 - 12:35, 2018

Dr. Masataka Ono (Keio University)
Dr. Shingo Sugiyama (Nihon University)
Mr. Yoshinosuke Hirakawa (Keio University)

This seminar is aimed at scientists in general, not only to mathematicians.

10:00-10:45 "Multiple zeta functions associated with 2-colored rooted trees" Masataka Ono
10:55-11:40 "Modular forms and trace formulas with applications to equidistributions of their Fourier coefficients" Shingo Sugiyama
11:50-12:35 "On a generalization of Dobinski's formula" Yoshinosuke Hirakawa

Venue: Seminar Room #160, 1F Main Research Building, RIKEN

Event Official Language: English

Symposium

Supported by iTHEMS

International Symposium on Quantum Fluids and Solids (QFS)

July 25 - 31, 2018

The International Symposium on Quantum Fluids and Solids (QFS) will be held at Ito International Research Center (IIRC) on Hongo campus of the University of Tokyo, Japan, from July 25 through 31, 2018. One of the sponsors of this conference is iTHEMS.

The QFS series started forty-three years ago making it one of the oldest series of international conferences in the field of low temperature physics. It has historically been focusing on physics of liquid and solid helium and hydrogen. But in this century its scope is expanding widely from laser cooled cold atoms to topological matters. At QFS2018 in Tokyo, this trend will be continued and with even more interdisciplinary aspects emphasized between the traditional subjects and those in broader physical systems.

Venue: Ito International Research Center (IIRC), Hongo Campus, The University of Tokyo

Event Official Language: English

Person of the Week

Dr. Shun Furusawa thumbnail

Self-introduction: Shun Furusawa

2018-06-25

Hello, I am Shun Furusawa, a special postdoctoral researcher of iTHEMS. I received a PhD at Waseda University in September 2013 and then I worked at NAOJ and FIAS as a posdoc. My research area is Nuclear Astrophysics. I am interested in birth, life, and death of various stars and related nuclear physics. At present, I am working on death of massive stars and birth of quark stars. I am looking forward to chatting and discussing with the iTHEMS members.

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