iTHEMS Biology Seminar by Prof. Takahiro Sakaue on July 1, 2021

On July 1st, Prof. Takahiro Sakaue (Aoyama Gakuin University) gave us a talk about chromatin dynamics in C. elegans embryos. He first introduced important factors for gene expression such as phase separation, topological constraints, and chromatin dynamics. After explaining how to see the chromatin dynamics under the microscope, he showed us interesting experimental results about the dependence of MSD on the nucleus radius. By considering polymer models, he showed that two kinds of typical length/time scales appear and discussed how the type of anomalous diffusion of chromatin is determined depending on the time/length scale. Moreover, he theoretically explained the observed nucleus-size dependence of MSD. We are grateful to Sakaue-san for the exciting talk!

Reported by Kyosuke Adachi