2021-02-25 Seminar Report

On 18th February, we invited Junichiro Iwasawa from the University of Tokyo, who gave a talk about the unique study to identify the evolutionary constraints of drug-resistance in Escherichia coli using automated high-throughput laboratory experiments. He first talked about the background of drug resistance evolution and about the well-known / novel resistance-conferring genes for E. coli that were elucidated from their data. He then moved on to the details of the data analyses and explained the combined method of random forest regression and principal component analysis on the multi-omics data. We enjoyed a long discussion on every single detail of the impressive work. We especially thank him for accepting our invitation despite the tight schedule with his dissertation. Thank you again for the great talk!
-Ryosuke Iritani

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