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Volume 344

iTHEMS Weekly News Letter

Hot Topic

Jeffrey Fawcett thumbnail

Farewell message from Jeffrey Fawcett

2025-02-25

Our colleague, Jeffrey Fawcett will move on to a new career as a Chief Scientist at Regional Fish Institute, Ltd. as of March 1st, 2025. We all will miss him and wish him the best of luck in his latest endeavor.
Here is a message from Jeffrey Fawcett:

I will be moving to Kyoto to work at a company called Regional Fish from March. I will also most likely have a joint position at Kyoto University at a lab funded by the company. The company was started a few years ago mostly be people from Kyoto University, Graduate School of Agriculture, where I did my study, and specializes in breeding and developing fish and aquatic species using genome editing and various other techniques. My task will mainly be to perform genomic data analysis for the company, although I will also have some freedom to pursue my own research. I am looking forward to the new challenge to utilize my expertise and work for a company whose I mission I can identify with.

I have been in iTHEMS for exactly 7 years, which say how much I enjoyed and appreciated the setup of iTHEMS. I remember some people telling me its their first time meeting a biologist, whereas I never imagined I would ever have the opportunity to enjoy talks on pure mathematics and theoretical physics. I would like to thank all the people involved in iTHEMS and hopefully I will be able to visit iTHEMS from time to time and keep up the connection.

Seminar Report

Visit by ASCENT-6E high school students on January 13, 2025

2025-02-25

On Monday, January 13th, 2025, we were glad to receive the visit of 15 high school students (13 female and 2 male) enrolled in the STELLA Program ASCENT-6E of Chiba University. The students, accompanied by the Program Director Prof. Jun Nomura, Prof. Atsushi Tsuji, and Program Coordinators Prof. Qian Wang and Prof. Hina Morishige, were welcome to a one-day workshop organized by iTHEMS members. The workshop consisted of a series of presentations in which iTHEMS members talked about some of the fundamental, yet unresolved, questions about our universe. We covered topics ranging from mathematics, biology, physics, and philosophy of science. The objective was to promote the curiosity of students towards science, using iTHEMS as an example of how scientists from different disciplines may interact and do research together under the same roof. We also took the chance to advertise the different RIKEN programs for young researchers and encouraged the students to follow their dreams of becoming professional scientists.

During lunchtime and the interactive sessions, we also enjoyed nice opportunities to converse directly with the students, listen to their particular interests, and answer their questions. This visit by the STELLA program ASCENT-6E students was an invaluable opportunity for us at iTHEMS to understand the current situation of young students, their motivations, and their innovative ideas. For the sake of promoting love for science, inclusivity in academia, and a closer interaction with society, we hope that we can create more bridges between the iTHEMS members and the young students in the future.

We are glad that the workshop was a success. Please see the webpage of STELLA Program ASCENT-6E to read some of the comments that students made regarding their visit to iTHEMS.

Reported by José Said Gutiérrez-Ortega

Seminar Report

Theories of Astrophysical Big Bangs 2025 on February 17, 2025

2025-02-25

The international workshop “Theories of Astrophysical Big Bangs 2025” was held at RIKEN from February 17 to 19. During the workshop, Daniel Kasen (UC Berkeley), who is currently on sabbatical at RIKEN, delivered a special lecture on supernovae and kilonovae. In addition, 25 invited talks were presented, allowing participants to share the latest advancements in the field of Astrophysical Big Bangs. The workshop also featured 33 poster presentations, showcasing the diverse range of research in the field and fostering extensive discussions among participants.

A total of 83 participants from six countries, including Japan, registered for the workshop. This event was supported by the JST ASPIRE project for top scientists: “RIKEN-Berkeley Mathematical Quantum Science Initiative”, which particularly contributed to strengthening research collaboration between RIKEN and UC Berkeley. The workshop is expected to serve as a catalyst for future joint research endeavors.

Reported by Shigehiro Nagataki

Upcoming Events

Workshop

RIKEN-Nara Women's University Joint Diversity Promotion Workshop 2025

March 3 (Mon) - 4 (Tue), 2025

The RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS) and the Faculty of Science at Nara Women's University are promoting a project to foster female researchers under the auspices of the RIKEN Diversity Promotion Office. As part of the program, 19 undergraduate and graduate students from Nara Women's University will visit several laboratories on the RIKEN Wako campus to ask questions about their research and hold workshops/presentations with iTHEMS researchers.

Organizers:
RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS)
Faculty of Science, Nara Women's University

Program:
13:50-15:15
RIBF Facility, RIKEN Nishina Center (RNC) (E01, Nishina RIBF Building)

15:30-16:30
RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS) (C01, Main Research Building, #359)
Introduction to iTHEMS: Tetsuo Hatsuda (iTHEMS Director)
Lecture and Q&A: Nagisa Hiroshima (iTHEMS)

16:45-18:00
RIKEN Center for Brain Science (CBS) (C56, Ikenohata Research Building, #316)
Laboratory for Sensorimotor Integration (Fumi Kubo, Team Leader)

18:30-21:00
Networking Session (C01, Research Building 3F)

9:15-10:30
RIKEN Center for Advanced Photonics (RAP) (C32, Laser Research Building, Mid Conference Room A)
Photonics Control Technology Team (Satoshi Wada, Team Leader)

10:45-12:00
RIKEN Center for Sustainable Resource Science (CSRS) (S01, Biological Science Research Building, S311)
Molecular Bioregulation Research Team (Shinya Hagihara, Team Leader)

Venue: RIKEN Wako Campus

Workshop

iTHEMS Cosmology Forum 3 - (P)reheating the primordial Universe

March 4 (Tue) - 5 (Wed), 2025

Seishi Enomoto (Postdoctoral Researcher, College of Engineering Science, Yokohama National University)
John T. Giblin (Professor, Department of Physics, Kenyon College, USA)
Kyohei Mukaida (Assistant Professor, Theory Center, High Energy Accelerator Research Organization (KEK))

iTHEMS Cosmology Forum Workshop is a series of short workshops, each focusing on an emerging topics in cosmology. The target audience is cosmologists, high-energy physicists and astronomers interested in learning about the subject, not just those who have already worked on the topic. The goal of the workshop is to provide working knowledge of the topic and leave dedicated time for discussions to encourage mutual interactions among participants.

The third workshop is devoted to the 'reheating' phase of the early Universe. Reheating bridges the gap between the (almost) empty universe at the end of cosmic inflation and the thermal state of particles, required for Big-Bang nucleosynthesis, and the events of the hot Big-Bang model as a whole, to unfold. It is expected to proceed in different stages starting with a violent parametric resonant creation of particles, dubbed preheating, followed by a redistribution of energy leading to a thermal state. This phase potentially hosts rich phenomenology such as the formation of topoligical defects e.g. solitons, generation of gravitiational wave, and so on. Yet, the very non-linear nature of reheating makes it notoriously hard to describe analytically, and even numerical simulations struggle to follow the whole sequence of events in a given model. Reheating studies have thus yet to reach the degree of compherensiveness and universality that the understanding of cosmic inflation has achieved.

This forum will consist of two events. The first, on March 4th, will be in conference format comprising scientific talks on research trends in (P)Reheating. The second, on March 5th, will be a tutorial on numerical aspects of reheating (both theory and hands-on with code) hosted by Tom Giblin of Kenyon College.

The workshop will be in English.

The workshops are organised by the iTHEMS Cosmology Forum working group, which is the successor of the Dark Matter Working Group at RIKEN iTHEMS.

Important dates:
Feb. 25th - Registration deadline
March 4th - Workshop Day (Room #435-437, Main Research Building 4F)
March 5th - Tutorial Day (Room #445-447, Main Research Building 4F)

Invited Speakers:
John T. Giblin - Kenyon College
Kyohei Mukaida - KEK
Seishi Enomoto - Yokohama National University

Organisers:
Kohei Hayashi, Nagisa Hiroshima, Derek Inman, Amaury Micheli, Ryo Namba

Venue: #435-437, 4F, Main Research Building, RIKEN / #445-447, 4F, Main Research Building, RIKEN

Event Official Language: English

Seminar

iTHEMS Biology Seminar

Density-dependent dispersal promotes female-biased sex allocation in viscous populations: From theory to experiment

March 4 (Tue) at 16:00 - 17:00, 2025

Chedhawat Chokechaipaisarn (Ph.D Student, School of Biology, University of St Andrews, UK)

A key prediction in sex allocation theory is that the optimal sex ratio is completely independent to the rate of dispersal. This result challenges the notion of any relationship between dispersal and sex ratio evolution. However, the invariant result is based on the assumption that an individual's dispersal behaviour is not modulated by population density. In this talk, I will explore how density-dependent dispersal impact upon the evolution of sex allocation in a viscous-population setting. Additionally, I will discuss the process of testing this prediction through experimental evolution in spider mites.

Venue: Hybrid Format (3F #359 and Zoom), Seminar Room #359, 3F Main Research Building, RIKEN

Event Official Language: English

Seminar

iTHEMS Biology Seminar

From the Andes to the Lab Bench: Genomic, Evolutionary, and Functional Insights into Amylase Gene Variation and Metabolic Adaptation

March 6 (Thu) at 16:00 - 17:00, 2025

Gokcumen Omer (Professor, Department of Biological Sciences, University at Buffalo, USA)

Our laboratory investigates how genomic structural variations (SVs) uniquely drive biological diversity and evolution, surpassing smaller-scale variations like single nucleotide polymorphisms. This talk highlights our work on the amylase locus, a rapidly evolving genomic region shaped by dietary adaptations, frequent duplications, and high mutation rates. I will discuss its convergent evolution across mammals, driven by natural selection linked to starch-rich diets, and describe how long-read sequencing uncovered the mutational mechanisms behind its rapid evolution. We also examine local positive selection in indigenous Andean populations with historically starch-rich diets and how these adaptations impact metabolic health. Finally, I will summarize functional experiments in transgenic mice and diabetic-prone Western Nile rats, relevant models for human metabolism, to investigate the broader metabolic roles of amylase gene duplications. This research provides a roadmap for studying complex SVs in evolution, offering insights into human adaptation and health.

Venue: via Zoom / Seminar Room #359, 3F Main Research Building, RIKEN

Event Official Language: English

Colloquium

iTHEMS Colloquium

Smart heuristics of a single-celled organism

March 7 (Fri) at 14:00 - 15:30, 2025

Toshiyuki Nakagaki (Professor, Research Institute for Electronic Science, Hokkaido University)

Although we rarely question how smart unicellular organisms are, it has become clear that unicellular organisms are smarter than we expected. In fact, various protozoa (unicellular eukaryotes) can take actions that are advantageous for their survival even in complex environments in the wild environments. In this talk, I will introduce some typical examples of smart behaviors in a protozoan amoeba (the plasmodium of Physarum polycephalum): (1) maze-solving, (2) formation of multi-functional transport network that mimics public transportation network among cities in Tokyo region, and so on. We will propose a mathematical model of these behaviors and extract the heuristics (simple rules of behavior) that give rise to their smartness. In general, we will discuss the future potential of research into the behavioral intelligence of protozoa.

References

  1. Research Project “Ethological Dynamics in Diorama Environments” 
  2. Toshiyuki Nakagaki, Hiroyasu Yamada & Ágota Tóth, Maze-solving by an amoeboid organism, Nature 407, 470 (2000), doi: 10.1038/35035159 
  3. Atsushi Tero, Seiji Takagi, Tetsu Saigusa, Kentaro Ito, Dan P. Bebber, Mark D. Fricker, Kenji Yumiki, Ryo Kobayashi, and Toshiyuki Nakagaki, Rules for Biologically Inspired Adaptive Network Design, Science 327(5964):439-42 (2010), doi: 10.1126/science.1177894 
  4. John S. MacNeil, Slimy, But Not Stupid 
  5. Philip Ball, Cellular memory hints at the origins of intelligence, Nature volume 451, 385 (2008), doi: 10.1038/451385a 
  6. Steve Nadis, Slime and fleas feature in Ig Nobel awards, Nature volume 455, pages 714–715 (2008), doi: 10.1038/455714b 
  7. Pete Wilton, Ig Nobel for slime networks 
  8. Ferris Jabr, How Brainless Slime Molds Redefine Intelligence [Video] 

Venue: Okochi Hall, 1F Laser Science Laboratory, RIKEN / via Zoom

Event Official Language: English

Conference

Meeting for Intersections of Nuclear and Other Researches

March 10 (Mon) - 11 (Tue), 2025

The purpose of this workshop (held in Japanese) is to promote interdisciplinary research by young researchers through exchanges among all fields of theoretical physics, including the nuclear physics, which is a boundary region between various fields.

Venue: #435-437, Main Research Building, RIKEN

Event Official Language: Japanese

Seminar

RIKEN Quantum Seminar

RIKEN Quantum hands-on workshop on QURI SDK for creating and executing quantum algorithms on various quantum computers and simulators

March 13 (Thu) at 15:00 - 17:30, 2025

This workshop will be a hands-on session on QURI SDK, following the RIKEN Quantum seminar by Andreas Thomasen (QunaSys) on January 27.
Even if you did not attend the previous seminar, please join us if you would like to learn how to use QURI SDK.

The workshop outline is as follows:

  1. General introduction to QURI SDK and its intended workflow
  2. Introduction to QURI VM with various virtual devices introduced
  3. Experimenting with surface code parameters in QURI VM
  4. Introduction to QURI Algo and algorithm components
  5. Introduction to various algorithms for early FTQC

This workshop will be a hybrid of on-site and Zoom, but we encourage you to attend on-site to learn how to use QURI SDK more clearly.
In addition to the instructor, QunaSys researchers will be available to help you directly.
The Zoom URL will be provided only to registered participants.
To participate, please fill out the registration form at the link above by March 3.

Organizers: Andreas Thomasen (QunaSys), Kentaro Wada (QunaSys), Shinichiro Fujii (RIKEN)

Venue: Seminar Room #359, 3F Main Research Building, RIKEN / via Zoom

Event Official Language: English

Seminar

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iTHEMS Biology Seminar

It’s about time! Daily rhythms in malaria infections matter for parasite survival and transmission

March 13 (Thu) at 17:00 - 18:00, 2025

Reece Sarah (Professor, University of Edinburgh, UK)

The Reece lab provides a unique perspective on parasites, examining their world within hosts and vectors (insects that transmit parasites). Working at the intersection of parasitology, chronobiology, and evolutionary ecology, our research asks: “what makes a successful parasite” and “what are their evolutionary limits”? Unlike most infection research, that focuses solely on genetics and molecular aspects, our approach considers parasites in their ecological and evolutionary contexts. This has enabled us to uncover the sophisticated strategies that malaria parasites possess, such as optimizing the balance between transmission and replication, strategic investment in each sex of transmission stages, and scheduling activities according to the time of day. By understanding how parasites navigate their challenging lifestyles and seize opportunities, we contribute to interventions that can outsmart parasites and reduce the risk of resistance evolution. Our findings extend beyond the laboratory, showcasing the potential of environmental research to curb the impact of parasitic infections, whether in humans, wildlife, livestock, or agriculture, and helping to protect ecosystems.

Venue: via Zoom

Event Official Language: English

Workshop

Integrated Innovation Building (IIB) venue photo

Third Workshop on Density Functional Theory: Fundamentals, Developments, and Applications (DFT2025)

March 25 (Tue) - 27 (Thu), 2025

The density functional theory (DFT) is one of the powerful methods to solve quantum many-body problems, which, in principle, gives the exact energy and density of the ground state. The accuracy of DFT is, in practice, determined by the accuracy of an energy density functional (EDF) since the exact EDF is still unknown. Currently, DFT has been used in many communities, including nuclear physics, quantum chemistry, and condensed matter physics, while the fundamental study of DFT, such as the first principle derivations of an accurate EDF and methods to calculate many observables from obtained densities and excited states, is still ongoing. However, there has been little opportunity to have interdisciplinary communication.

On December 2022, we had the first workshop on this series (DFT2022) at Yukawa Institute for Theoretical Physics, Kyoto University, and several interdisciplinary discussions and collaborations were started. On February 2024, we had the second workshop on this series (DFT2024) at RIKEN Kobe Campus, and more stimulated discussion occured. To keep and extend collaborations, we organize the third workshop. Since the third workshop, we extend the scope of the workshop to the development and application of DFT as well. In this workshop, the current status and issues of each discipline will be shared towards solving these problems by meeting together among researchers in mathematics, nuclear physics, quantum chemistry, and condensed matter physics.

This workshop mainly comprises lectures/seminars on cutting-edge topics and discussion, while sessions composed of contributed talks are also planned.

Venue: 8F, Integrated Innovation Building (IIB), Kobe Campus, RIKEN / via Zoom

Event Official Language: English

Seminar

Quantum Gravity Gatherings

Stability of nonsingular black holes

March 27 (Thu) at 15:00 - 16:30, 2025

Shinji Tsujikawa (Professor, Graduate School of Advanced Science and Engineering, Faculty of Science and Engineering, Waseda University)

We show that nonsingular black holes (BHs) realized in nonlinear electrodynamics are always prone to Laplacian instability around the center because of a negative squared sound speed in the angular direction. This is the case for both electric and magnetic BHs, where the instability of one of the vector-field perturbations leads to enhancing a dynamical gravitational perturbation in the even-parity sector. Thus, the background regular metric is no longer maintained in a steady state. We also generalize our analysis to the case in which a scalar field is present besides the U(1) gauge field and find no explicit examples of linearly stable nonsingular BHs. Our results suggest that the construction of regular BHs without instabilities is generally challenging within the scheme of classical field theories.

Venue: Seminar Room #359, 3F Main Research Building, RIKEN / via Zoom

Event Official Language: English

Seminar

iTHEMS Seminar

Artificial Intelligence and Neuroscience

April 11 (Fri) at 14:00 - 15:30, 2025

Junichi Chikazoe (Professor, Center for Brain,Mind and KANSEI Sciences Research, Hiroshima University)

Recent advancements in artificial intelligence have led to various discoveries in the field of neuroscience. For example, it has been demonstrated that the information on orientation columns in the visual cortex and the basic taste information in the gustatory cortex can be extracted by applying machine learning to relatively low-resolution functional MRI data. Additionally, intriguing findings have emerged, such as the information processing structures of artificial neural circuits—designed independently of the brain—showing similarities to those of biological neural networks.
In this talk, I will discuss the applications of artificial intelligence in neuroscience and explore future directions in this field.

Venue: Seminar Room #359, 3F Main Research Building, RIKEN / via Zoom

Event Official Language: English

Upcoming Visitors

March 3 (Mon) - 6 (Thu), 2025

Tomo Takahashi

Professor, Department of Physics, Saga University

Visiting Place: RIKEN Wako Campus

March 3 (Mon) - 8 (Sat), 2025

Chedhawat Chokechaipaisarn

Ph.D Student, School of Biology, University of St Andrews, UK

Visiting Place: RIKEN Wako Campus

March 4 (Tue) - 7 (Fri), 2025

John T. Giblin

Professor, Department of Physics, Kenyon College, USA

Visiting Place: RIKEN Wako Campus

March 6 (Thu) - 7 (Fri), 2025

Gokcumen Omer 

Professor, Department of Biological Sciences, University at Buffalo, USA

Visiting Place: RIKEN Wako Campus

Paper of the Week

Week 5, February 2025

2025-02-27

Title: Detection of molecular clouds in the PeVatron candidate source LHAASO J0341+5258 by the Nobeyama 45-m radio telescope
Author: Naomi Tsuji, Shunya Takekawa, Kaya Mori, Alison Mitchell, Shuo Zhang, Priyadarshini Bangale, Stephen DiKerby, Tülün Ergin, Jooyun Woo, Samar Safi-Harb, Shinta Kausya
arXiv: 2502.15432

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